A 54-year-old American woman who underwent both a pig kidney transplant and a heart pump implant has died. Lisa Pisano was near death due to kidney and heart failure when NYU Langone Health surgeons performed the surgery on her in April.

At first, the New Jersey woman appeared to be recovering well, but about 47 days later, doctors had to remove the pig's kidney and put her back on dialysis. Despite dialysis and a heart pump implant, surgeons said. Pisano eventually died in hospital on Sunday.

One of Pisano's surgeons said: "Lisa has helped us move closer to a future where no one has to die so that someone else can live." "He will forever be remembered for his bravery."

Pisano was the second patient to receive a genetically modified pig kidney. The first, Richard "Rick" Slimman, received his transplant at a Massachusetts hospital and died in early May, nearly two months later.

More than 100,000 people are on the US transplant waiting list, most of whom need a kidney, and thousands die waiting. Several biotech companies are genetically modifying pigs to make their organs more human-like and less likely to be rejected by the human immune system.

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